Zhengxing Wu, Jingjie Meng, Huikang Liu, Yunyi Li, Xiao Zhang, and Wanbin Zhang*, “Multisite programmable functionalization of alkenes via controllable alkene isomerization".  Nat. Chem. 2023, DOI: 10.1038/s41557-023-01209-x.

Liang Tang, Yicong Luo, Cheng Sheng, Fang Xie*, and Wanbin Zhang*,  Cu-Catalyzed Asymmetric Kinetic Boron Conjugate Addition of γ-Substituted α,β-Unsaturated γ-Lactams. Angew. Chem. Int. Ed. 2023, 62, e202304640. DOI: 10.1002/anie.202304640.

 (Hot paper)

Tiantian Chen, Yashi Zou, Yanhua Hu, Zhenfeng Zhang, Hao Wei, Liangming Wei, and Wanbin Zhang*,  Cobalt-Catalyzed Efficient Convergent Asymmetric Hydrogenation of E/Z-Enamides. Angew. Chem. Int. Ed. 2023, 62, e202303488. DOI: 10.1002/anie.202303488.

 (Hot paper)

Yanhua Hu, Yashi Zou, Huiwen Yang, Haotian Ji, Yue Jin, Zhenfeng Zhang,* Yangang Liu, and Wanbin Zhang*,  Precise Synthesis of Chiral Z-Allylamides by Cobalt-Catalyzed Asymmetric Sequential Hydrogenations. Angew. Chem. Int. Ed. 2023, 62, e202217871. DOI: 10.1002/anie.202217871.

Ling Zhao, Yicong Luo, Junzhe Xiao, Xiaohong Huo, Shengming Ma,* and Wanbin Zhang*, Stereodivergent Synthesis of Allenes with α,β-Adjacent Central Chiralities Empowered by Synergistic Pd/Cu Catalysis. Angew. Chem. Int. Ed. 2023, 62, e202218146. DOI: 10.1002/anie.202218146.

 (Hot paper)

Hanlin Wei, Hao Chen, Jianzhong Chen*, Ilya. D. Gridnev,* and Wanbin Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation of α-Substituted Vinylphosphonates and Diarylvinylphosphine Oxides. Angew. Chem. Int. Ed. 2023, 62, e202214990. DOI: 10.1002/anie.202214990.

Yunnan Xu, Yicong Luo, Jianxun Ye, Yu Deng, Delong Liu, and Wanbin Zhang*, Rh-Catalyzed Sequential Asymmetric Hydrogenations of 3-Amino-4-Chromones via an Unusual Dynamic Kinetic Resolution Process. J. Am. Chem. Soc. 2022, 144, 20078-20089. DOI: 10.1021/jacs.2c09266 

Feng Gao, Jing Li, Tanveer Ahmad, Yicong Luo, Zhenfeng Zhang, Qianjia Yuan, Xiaohong Huo, Tao Song, and Wanbin Zhang*, Sci. China Chem. 2022, 65, 1968-1977. DOI: 10.1007/s11426-022-1387-7. 

Mo Wang,§ Zhenfeng Zhang,§ and Wanbin Zhang*, Design, Synthesis and Application of Chiral Bicyclic Imidazole Catalysts. Acc. Chem. Res. 2022, 55, 2708-2727. DOI: 10.1021/acs.accounts.2c00455.

 (Invited Account)

Xiaohong Huo, Guanlin Li, Xi Wang, and Wanbin Zhang*, Bimetallic Catalysis in Stereodivergent Synthesis. Angew. Chem. Int. Ed. 2022, 61, e202210086. DOI: 10.1002/anie.202210086.

(Invited Review)

Biwen Li, Jianzhong Chen, Dan Liu, Ilya D. Gridnev, and Wanbin Zhang*, Nickel-catalysed asymmetric hydrogenation of oximes. Nat. Chem. 2022, online. DOI: 10.1038/s41557-022-00971-8. 

Youbin Peng, Chongyu Han, Yicong Luo, Guanlin Li, XiaohongHuo, and Wanbin Zhang*, Nickel/Copper-Cocatalyzed Asymmetric Benzylation of Aldimine Esters for the Enantioselective Synthesis of α-Quaternary Amino Acids. Angew. Chem. Int. Ed. 2022, 61, e202203448. DOI:10.1002/anie.202203448.

 (Hot paper)

Muxing Zhou, Yashi Zou, Lu Zhang, Zhenfeng Zhang, and Wanbin Zhang*, Chiral Bicyclic Imidazole-Catalyzed Direct Enantioselective C-Acetylation of Indolones. CCS Chem. 2022, accepted. DOI: 10.31635/ccschem.022.202201782.

Cheng Sheng, Zheng Ling, Yicong Luo, and Wanbin Zhang*, Cu-catalyzed asymmetric addition of alcohols to β,γ-alkynyl-α-imino esters for the construction of linear chiral N,O-ketals. Nat. Commun. 2022, 13, 400. DOI: 10.1038/s41467-022-28002-7.

Youbin Peng, Xiaohong Huo, Yicong Luo, Liang Wu, and Wanbin Zhang*, Enantio- and Diastereodivergent Synthesis of Spirocycles through Dual-Metal-Catalyzed [3+2] Annulation of 2-Vinyloxiranes with Nucleophilic Dipoles. Angew. Chem. Int. Ed. 2021, 60, 24941-24949. DOI: 10.1002/anie.202111842.

(Hot paper)

Yunnan Xu, Delong Liu, Yu Deng, Yi Zhou, and Wanbin Zhang*, Rh-Catalyzed Asymmetric Hydrogenation of 3-Benzoylaminocoumarins for the Synthesis of Chiral 3-Amino Dihydrocoumarins. Angew. Chem. Int. Ed. 2021, 60, 23602-23607. DOI: 10.1002/anie.202110286.

Jiacheng Zhang, Xiaohong Huo, Junzhe Xiao, Ling Zhao, Shengming Ma*, and Wanbin Zhang*, Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis. J. Am. Chem. Soc. 2021, 143, 12622-12632. DOI: 10.1021/jacs.1c05087.

Jian Zhang, Tiantian Chen, Yuanhao Wang, Fengfan Zhou, Zhenfeng Zhang*, Ilya D. Gridnev*, and Wanbin Zhang*, Asymmetric Hydrogenation of γ-Branched Allylamines for the Efficient Synthesis of γ-Chirogenic Amines. Nat. Sci. 2021, e10021. DOI: 10.1002/ntls.10021.

(Cover Picture Paper)

Yanhua Hu, Zhenfeng Zhang, Yangang Liu, and Wanbin Zhang*, Cobalt-Catalyzed Chemo- and Enantioselective Hydrogenation of Conjugated Enynes. Angew. Chem. Int. Ed. 2021, 60, 16989-16993. DOI: 10.1002/anie.202106566.

Xiaohong Huo, Ling Zhao, Yicong Luo, Yue Wu, Yuwen Sun, Guanlin Li, Tatiana Gridneva, Jiacheng Zhang, Yong Ye, and Wanbin Zhang*, Stereodivergent Pd/Cu Catalysis for Asymmetric Desymmetric Alkylation of Allylic Geminal Dicarboxylates. CCS Chem. 2021, 3, 1933-1944. DOI: 10.31635/ccschem.021.202101044.

Chong Liu, Jing Yuan, Zhenfeng Zhang*, Ilya D. Gridnev, and Wanbin Zhang*, Asymmetric Hydroacylation Involving Alkene Isomerization for the Construction of C3-Chirogenic Center. Angew. Chem. Int. Ed. 2021, 60(16), 8997-9002. DOI: 10.1002/anie.202017190 (Very Important Paper)

Muxing Zhou, Tatiana Gridneva, Zhenfeng Zhang, Ende He, Yangang Liu, and Wanbin Zhang*, Chiral Bicyclic Imidazole-Catalyzed Acylative Dynamic Kinetic Resolution for the Synthesis of Chiral Phthalidyl Esters. Angew. Chem. Int. Ed. 2021, 60(3), 1641-1645. DOI: 10.1002/anie.202012445 (Highlighted by SYNFACTS 2020, 16, 1466; Very Important Paper)

Dan Liu, Bowen Li, Jianzhong Chen, Ilya D. Gridnev, Deyue Yan, and Wanbin Zhang*, Ni-Catalyzed Asymmetric Hydrogenation of N-Aryl Imino Esters for the Efficient Synthesis of Chiral α-Aryl Glycines. Nat. Commun. 2020, 11, 5935. DOI: 10.1038/s41467-020-19807-5 (Highlighted by SYNFACTS 2021, 17, 0165)

Mo Wang, Lu Zhang, Xiaohong Huo, Zhenfeng Zhang, Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, and Wanbin Zhang*, Catalytic Asymmetric Synthesis of the anti-COVID-19 Drug Remdesivir. Angew. Chem. Int. Ed. 2020, 59(47), 20814-20819. DOI: 10.1002/anie.202011527 (Highlighted by SYNFACTS 2020, 16, 1350; Very Important Paper; Frontispiece)

Rui He, Xiaohong Huo, Ling Zhao, Feijun Wang, Liyin Jiang, Jian Liao*, and Wanbin Zhang*, Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates. J. Am. Chem. Soc. 2020, 142(18), 8097-8103. DOI: 10.1021/jacs.0c02150 (Highlighted by 有机化学 2020, 40, 2161)

Guanlin Li, Xiaohong Huo, Xieyang Jiang, and Wanbin Zhang*, Asymmetric Synthesis of Allylic Compounds via Hydrofunctionalisation and Difunctionalisation of Dienes, Allenes, and Alkynes. Chem. Soc. Rev. 2020, 49(7), 2060-2118. DOI: 10.1039/c9cs00400a (ESI Highly Cited Paper; Inside Front Cover)

Yawen Hu, Jianzhong Chen, Bowen Li, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates. Angew. Chem. Int. Ed. 2020, 59(13), 5371-5375. DOI: 10.1002/anie.201916534

Liang Wu, Guoqiang Yang, and Wanbin Zhang*, Ni-Catalyzed Enantioconvergent Coupling of Epoxides with Alkenylboronic Acids: Construction of Oxindoles Bearing Quaternary Carbons. CCS Chem. 2020, 2(2), 623-631. DOI: 10.31635/ccschem.019.201900064

Yanhua Hu, Zhenfeng Zhang, Jian Zhang, Yangang Liu, Ilya D. Gridnev, and Wanbin Zhang*, Cobalt-Catalyzed Asymmetric Hydrogenation of C=N Bonds Enabled by Assisted Coordination and Nonbonding Interactions. Angew. Chem. Int. Ed. 2019, 58(44), 15767-15771. DOI: 10.1002/anie.201909928 (Highlighted by SYNFACTS 2019, 15, 1381 and selected as Synfact of the month)

Jian Zhang, Jia Jia, Xincheng Zeng, Yuanhao Wang, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, Chemo- and Enantioselective Hydrogenation of α-Formyl Enamides: An Efficient Access to Chiral α-Amido Aldehydes. Angew. Chem. Int. Ed. 2019, 58(33), 11505-11512. DOI: 10.1002/anie.201905263 (Highlighted by Advances In ENGINEERING; Very Important Paper)

Bowen Li, Jianzhong Chen, Zhenfeng Zhang, Ilya D. Gridnev, and Wanbin Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines. Angew. Chem. Int. Ed. 2019, 58(22), 7329-7334. DOI: 10.1002/anie.201902576 (Very Important Paper; Inside Back Cover)

Jianzhong Chen, Zhenfeng Zhang, Bowen Li, Feilong Li, Yulin Wang, Min Zhao, Ilya D. Gridnev, Tsuneo Imamoto, and Wanbin Zhang*, Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of Sterically Hindered N-Tosylimines. Nat. Commun. 2018, 9, 5000. DOI: 10.1038/s41467-018-07462-w

Xuezhen Kou, Qihang Shao, Chenghao Ye, Guoqiang Yang*, and Wanbin Zhang*, Asymmetric Aza-Wacker-Type Cyclization of N-Ts Hydrazine-Tethered Tetrasubstituted Olefins: Synthesis of Pyrazolines Bearing One Quaternary or Two Vicinal Stereocenters. J. Am. Chem. Soc. 2018, 140(24), 7587-7597. DOI: 10.1021/jacs.8b02865 (Highlighted by SYNFACTS 2018, 14, 0840)

Mao Quan, Xiaoxiao Wang, Liang Wu, Ilya D. Gridnev, Guoqiang Yang*, and Wanbin Zhang*, Ni(II)-Catalyzed Asymmetric Alkenylations of Ketimines. Nat. Commun. 2018, 9, 2258. DOI: 10.1038/s41467-018-04645-3

Guoqiang Yang and Wanbin Zhang*, Renaissance of Pyridine-Oxazolines as Chiral Ligands for Asymmetric Catalysis. Chem. Soc. Rev. 2018, 47(5), 1783-1810. DOI: 10.1039/c7cs00615b (Back Cover)

Xiaohong Huo, Jiacheng Zhang, Jingke Fu, Rui He, and Wanbin Zhang*, Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters. J. Am. Chem. Soc. 2018, 140(6), 2080-2084. DOI: 10.1021/jacs.8b00187 (Highlighted by Organic Chemistry Portal; ESI Highly Cited Paper)

Xiaohong Huo, Rui He, Jingke Fu, Jiacheng Zhang, Guoqiang Yang, and Wanbin Zhang*, Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis. J. Am. Chem. Soc. 2017, 139(29), 9819-9822. DOI: 10.1021/jacs.7b05460

(Highlighted by SYNFACTS 2017, 13, 1049 and 有机化学 2017, 37, 2454)

Zhenfeng Zhang, Nicholas A. Butt, and Wanbin Zhang*, Asymmetric Hydrogenation of Nonaromatic Cyclic Substrates. Chem. Rev. 2016, 116(23), 14769-14827. DOI: 10.1021/acs.chemrev.6b00564 (ESI Highly Cited Paper)

Xiaohong Huo, Rui He, Xiao Zhang, and Wanbin Zhang*, An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones. J. Am. Chem. Soc. 2016, 138(35), 11093-11096. DOI: 10.1021/jacs.6b06156 (Highlighted by SYNFACTS 2016, 12, 1153 and selected as Front Cover and Synfact of the month; Highlighted by Org. Process. Res. Dev. 2016, 20, 1691)

Jianzhong Chen, Zhenfeng Zhang, Delong Liu, and Wanbin Zhang*, Palladium-Catalyzed Chemo- and Enantioselective C−O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis. Angew. Chem. Int. Ed. 2016, 55(29), 8444-8447. DOI: 10.1002/anie.201603590

(Highlighted by SYNFACTS 2016, 12, 1047 and 有机化学 2016, 36, 1970)

Nicholas A. Butt and Wanbin Zhang*, Transition Metal-Catalyzed Allylic Substitution Reactions with Unactivated Allylic Substrates. Chem. Soc. Rev. 2015, 44(22), 7929-7967. DOI: 10.1039/c5cs00144g (ESI Highly Cited Paper; Front Cover)

Qiupeng Hu, Zhenfeng Zhang, Yangang Liu, Tsuneo Imamoto, and Wanbin Zhang*, ZnCl2-Promoted Asymmetric Hydrogenation of β-Secondary-Amino Ketones Catalyzed by a P-Chiral Rh–Bisphosphine Complex. Angew. Chem. Int. Ed. 2015, 54(7), 2260-2264. DOI: 10.1002/anie.201411384

(Highlighted by SYNFACTS 2015, 11, 0411 and 有机化学 2015, 35, 1187)

Xun-Xiang Guo*, Da-Wei Gu, Zhengxing Wu, and Wanbin Zhang*, Copper-Catalyzed C–H Functionalization Reactions: Efficient Synthesis of Heterocycles. Chem. Rev. 2015, 115(3), 1622-1651. DOI: 10.1021/cr500410y

(入选2015年中国百篇最具影响国际学术论文; ESI Highly Cited Paper)

Xiaohong Huo, Guoqiang Yang, Delong Liu, Yangang Liu, Ilya D. Gridnev*, and Wanbin Zhang*, Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study. Angew. Chem. Int. Ed. 2014, 53(26), 6776-6780. DOI: 10.1002/anie.201403410

Yuanyuan Liu, Ilya D. Gridnev*, and Wanbin Zhang*, Mechanism of the Asymmetric Hydrogenation of Exocyclic α,β-Unsaturated Carbonyl Compounds with an Iridium/BiphPhox Catalyst: NMR and DFT Studies. Angew. Chem. Int. Ed. 2014, 53(7), 1901-1905. DOI: 10.1002/anie.201309677

Jianzhong Chen, Delong Liu, Nicholas Butt, Chao Li, Dongyang Fan, Yangang Liu, and Wanbin Zhang*, Palladium-Catalyzed Asymmetric Hydrogenation of α-Acyloxy-1-arylethanones. Angew. Chem. Int. Ed. 2013, 52(44), 11632-11636. DOI: 10.1002/anie.201306231

(Highlighted by SYNFACTS 2014, 10, 0064 and 有机化学 2013, 33, 2637)

Guoqiang Yang and Wanbin Zhang*, A Palladium-Catalyzed Enantioselective Addition of Arylboronic Acids to Cyclic Ketimines. Angew. Chem. Int. Ed. 2013, 52(29), 7540-7544. DOI: 10.1002/anie.201302861 (Highlighted by SYNFACTS 2013, 9, 1085)

Yuanyuan Liu and Wanbin Zhang*, Iridium-Catalyzed Asymmetric Hydrogenation of α-Alkylidene Succinimides. Angew. Chem. Int. Ed. 2013, 52(8), 2203-2206. DOI: 10.1002/anie.201209126 (Highlighted by SYNFACTS 2013, 9, 0506)

Guoqiang Yang, Chaoren Shen, and Wanbin Zhang*, An Asymmetric Aerobic Aza-Wacker-Type Cyclization: Synthesis of Isoindolinones Bearing Tetrasubstituted Carbon Stereocenters. Angew. Chem. Int. Ed. 2012, 51(36), 9141-9145. DOI: 10.1002/anie.201203693 (Highlighted by SYNFACTS 2012, 8, 1185)

Xiaohu Zhao, Delong Liu, Hui Guo, Yangang Liu, and Wanbin Zhang*, C–N Bond Cleavage of Allylic Amines via Hydrogen Bond Activation with Alcohol Solvents in Pd-Catalyzed Allylic Alkylation of Carbonyl Compounds. J. Am. Chem. Soc. 2011, 133(48), 19354-19357. DOI: 10.1021/ja209373k (Highlighted by SYNFACTS 2012, 8, 0182 and Organic Chemistry Portal)

Zhenfeng Zhang, Fang Xie, Jia Jia, and Wanbin Zhang*, Chiral Bicycle Imidazole Nucleophilic Catalysts: Rational Design, Facile Synthesis, and Successful Application in Asymmetric Steglich Rearrangement. J. Am. Chem. Soc. 2010, 132(45), 15939-15941. DOI: 10.1021/ja109069k (Highlighted by SYNFACTS 2011, 7, 0098 and 有机化学 2011, 31, 274)